High iron in pregnancy: what are the symptoms and what does it involve?
Controlling normal levels of iron in the blood during pregnancy is important for […]
What should you do in cases of iron deficiency anaemia during pregnancy? What are the iron values that need to be kept under control? Let’s examine the causes and symptoms of sideropenic anaemia (iron deficiency anaemia) during pregnancy.
Haemoglobin is a protein present in red blood cells and allows them to transport oxygen (O2) from the lungs to the tissues and carbon dioxide (CO2) from peripheral tissues to the lungs. Anaemia occurs when there is a reduction in haemoglobin below normal levels.
The normal values of haemoglobin (Hb) in the blood are as follows:
Men: 13.4 – 17.5 g/dL
Women: 12 – 15.5 g/dL
Pregnant women: 11 – 14 g/dL
Given that the synthesis of haemoglobin is regulated by the amount of iron in the blood, a reduction in the amount of haemoglobin can also occur if there is an iron deficiency in the body. This type of anaemia is known as sideropenic anaemia because it is caused by a deficiency of iron in the body.
In addition to iron deficiency anaemia, there are other types of anaemia, not always related to an iron deficiency in the blood. Some anaemias such as thalassaemias (e.g., Mediterranean anaemia, Fanconi anaemia or sickle-cell anaemia) have genetic causes, whilst in other cases, anaemias can be caused by autoimmune diseases, tumours or infections (e.g., malaria). From here on, we will deal specifically with iron deficiency anaemia.
An iron deficiency can be caused by:
In most cases, iron deficiency is a condition that sets in slowly. The body puts in place various mechanisms to combat sideropenia and to maintain the normal blood values of iron. However, when the iron reserves in the body are not sufficient to maintain the balance of this mineral in the body, we can see a progressive reduction of sideropenia (concentration of circulating iron related to transferrin) and ferritinaemia. Another value that is monitored in order to assess the blood iron level (the balance and metabolism of iron in the body) is that of transferrin, a protein that binds the iron and transports it into the body.
Iron deficiency anaemia can occur without relevant clinical symptoms and is detected through blood tests. This happens because it is often a condition that sets in slowly and, until the iron reserves in the body are significantly reduced, the characteristic symptoms do not appear. Pregnancy requires an increased bodily need for iron and, therefore, it is possible that a previous iron deficiency may become more pronounced during the gestation period and typical symptoms of iron deficiency anaemia emerge:
During pregnancy, it is particularly important to keep blood levels of iron and haemoglobin under control to prevent the development of sideropenic anaemia.
Low haemoglobin values can lead to fatigue and asthenia. An iron deficiency in the mother, especially in the last trimester of pregnancy, can also be the cause of reduced iron deposits in the unborn child.
In cases of sideropenia during pregnancy, the doctor will assess the most suitable therapy to bring the iron values in the body back to normal, through a diet with iron-rich foods and any specific food supplements.